Tour Grand Canyon National Park in the Afternoon.Here is our preferred itinerary for a two-day trip to these locations. Be aware that spending two days to see them is still going to put you on a tight schedule, you will get up early, get in late, and have a lot of driving to do.īecause of the threat of large animals on the road, it is best to avoid driving at night. A much better alternative to the above sleep-deprived dash through the desert is to spend an extra day and stay overnight in Arizona before coming back to Las Vegas.